Mysterious Commonplace, The: A Life In Science: A Life in Science

"Acclaimed biomedical scientist Charles DeLisi tells the story of the rewards and frustrations of a life in science, informed and influenced by a passion for poetry. The memoir spans half a century beginning in grade school when we find a painfully shy boy deeply affected by the profoundly saddening sight of trees and woods in his beloved Bronx neighborhood being displaced by tons of steel and concrete. The reader is taken inside the mind of a complex non-conformist as he struggles with personal tragedy and ambivalence and moves from physics to history back to physics, and eventually into a career as a biomedical scientist. Among the most important parts of the memoir are his personal recollections of the years as director of the Department of Energy's Health and Environmental Programs when he fought the mighty battles that would move two Federal Agencies and place the Human Genome Project, including a unique ethical component, on the National Agenda. We watch an uncannily successful strategist and leader - who sees himself as an ordinary person, distinguished only by an intense passion for science - as he and his colleagues successfully engage Congressmen, his superiors at the DOE, and scientists of different backgrounds. The story closes where it began, with environmental change dominating the emotional landscape, as he and his colleagues struggle to fight the battle against a changing climate"--
The Mysterious Commonplace is a narrative memoir which begins in grade school, when my interest in science was influenced by the chance reading of an unusual book, an uncle who asked provocative questions about common occurrences, and the painful experience of watching my neighborhood change from dense woods to cement. The story traces my educational path from physics to history to physics, and then to a career as a biomedical scientist and policy setter caught up with big ideas. It recounts the fierce initial pushback as I moved to launch the Human Genome Project, and reflects on the ethical dilemmas raised by the Project, and more generally on the ethical dilemmas resurrected by modern technology. The narrative moves on through my years of Dean of a College, my role in expanding the field of biomedical engineering, and my reflections on what the US needs to do to maintain technological leadership, while at the same time assuring that our technological innovations are used to benefit the people of the world. It concludes with my return to where I started, picturing the transformation of the neighborhood of my youth, as I recalled lines from Inversnaid, and came to realize that genomics might help mitigate one of the most serious challenges of our age, climate change.The broader context of the narrative is about a life in science; it's about people: the influence of friends and family, the deep satisfaction that comes from being part of a diverse and collaborative global community; the inspirational and humbling experience of having immensely talented friends and colleagues; the deep sense of appreciation for, and admiration of, the kindness of encouraging mentors, knowing that you could not have traveled nearly as far without their support; and the feeling of fulfillment that comes from participating in the growth of generations of students as they become colleagues — much as you feel as you watch the growth of your own children. Finally, the narrative is a portrayal of science as an international social enterprise that strikes a remarkably productive balance between fierce competition and deep collaboration, without which neither its global nor personal rewards can be achieved. It's a balance our politicians would do well to study.